H Steve White Selected Research

Galanin Receptors (Galanin Receptor)

1/2017	Preclinical evaluation of intravenous NAX 810-2, a novel GalR2-preferring analog, for anticonvulsant efficacy and pharmacokinetics.
3/2016	The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission.
1/2015	Analgesic properties of a peripherally acting and GalR2 receptor-preferring galanin analog in inflammatory, neuropathic, and acute pain models.
2/2010	Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery.
4/2009	Developing novel antiepileptic drugs: characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models.
3/2009	Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

H Steve White Research Topics

Disease

64	Epilepsy (Aura) 01/2022 - 02/2002
62	Seizures (Absence Seizure) 01/2022 - 02/2002
9	Status Epilepticus (Complex Partial Status Epilepticus) 12/2021 - 02/2007
9	Pain (Aches) 01/2019 - 01/2011
7	Drug Resistant Epilepsy 01/2022 - 12/2006
6	Partial Epilepsies (Epilepsy, Partial) 11/2020 - 02/2005
6	Temporal Lobe Epilepsy 01/2019 - 05/2007
6	Infections 03/2017 - 07/2010
4	Inflammation (Inflammations) 03/2017 - 06/2008
3	Gliosis 12/2021 - 03/2010
3	Myoclonic Epilepsies (Myoclonic Encephalopathy) 11/2020 - 09/2009
3	Generalized Epilepsy 11/2020 - 05/2007
3	Nervous System Diseases (Neurological Disorders) 01/2019 - 06/2006
3	Virus Diseases (Viral Diseases) 07/2011 - 03/2010
2	Neoplasms (Cancer) 01/2019 - 01/2015
2	Lennox Gastaut Syndrome 10/2018 - 10/2016
2	Epileptic Syndromes 10/2018 - 07/2008
2	Hyperglycemia 01/2017 - 04/2015
2	Spasm (Spasms) 01/2017 - 01/2014
2	Infantile Spasms (West Syndrome) 01/2017 - 01/2014
2	Migraine Disorders (Migraine) 09/2016 - 04/2005
2	Acute Pain 01/2015 - 01/2015
2	Benign Neonatal Epilepsy (Benign Familial Neonatal Convulsions) 07/2009 - 07/2008
2	Brain Injuries (Brain Injury) 01/2009 - 05/2004
2	Neural Tube Defects (Exencephaly) 01/2007 - 02/2002
1	Brain Diseases (Brain Disorder) 01/2022
1	Exanthema (Rash) 01/2021
1	Stroke (Strokes) 01/2021
1	COVID-19 11/2020

Drug/Important Bio-Agent (IBA)

35	Anticonvulsants (Antiepileptic Drugs)IBA 11/2020 - 02/2002
15	Pharmaceutical PreparationsIBA 11/2020 - 05/2007
11	GalaninIBA 01/2019 - 12/2008
10	Pentylenetetrazole (Metrazol)IBA 01/2022 - 02/2002
7	Kainic Acid (Kainate)IBA 12/2021 - 05/2007
6	GABA Plasma Membrane Transport ProteinsIBA 07/2020 - 10/2004
6	Valproic Acid (Depakote)FDA LinkGeneric 01/2017 - 02/2002
6	Galanin Receptors (Galanin Receptor)IBA 01/2017 - 03/2009
6	NeuropeptidesIBA 01/2015 - 12/2008
5	gamma-Aminobutyric Acid (GABA)IBA 07/2020 - 12/2006
5	EF1502IBA 07/2020 - 02/2005
5	Analgesics (Analgesic Drugs)IBA 01/2019 - 01/2011
5	BicucullineIBA 02/2015 - 02/2002
4	Betaine (C.B.B.)FDA Link 07/2020 - 10/2004
4	Tiagabine (Gabitril)FDA Link 07/2020 - 08/2002
4	Carbamazepine (Tegretol)FDA LinkGeneric 01/2019 - 07/2013
4	Minocycline (Cyclops)FDA LinkGeneric 01/2018 - 07/2011
4	Lamotrigine (Lamictal)FDA LinkGeneric 01/2018 - 01/2003
4	Messenger RNA (mRNA)IBA 03/2017 - 03/2010
3	CenobamateIBA 01/2021 - 11/2020
3	CarrageenanIBA 01/2019 - 02/2013
3	CannabidiolIBA 01/2019 - 10/2018
3	NAX 5055IBA 01/2019 - 04/2009
3	Phenytoin (Dilantin)FDA LinkGeneric 01/2018 - 03/2007
3	Formaldehyde (Formol)FDA Link 01/2017 - 05/2012
3	CytokinesIBA 01/2017 - 07/2011
3	ConvulsantsIBA 03/2016 - 05/2007
3	PicrotoxinIBA 02/2015 - 05/2007
3	Potassium Channels (Potassium Channel)IBA 07/2013 - 07/2008
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 06/2012 - 03/2004
3	Interleukin-6 (Interleukin 6)IBA 10/2011 - 03/2010
3	Topiramate (Topamax)FDA LinkGeneric 04/2005 - 01/2003
2	Proteins (Proteins, Gene)FDA Link 12/2021 - 03/2017
2	Felbamate (Felbatol)FDA Link 01/2021 - 12/2006
2	ezogabine (retigabine)IBA 01/2021 - 07/2013
2	CarbamatesIBA 01/2021 - 11/2020
2	SolutionsIBA 11/2020 - 10/2018
2	Levetiracetam (Keppra)FDA LinkGeneric 01/2019 - 01/2017
2	Glutamate Receptors (Glutamate Receptor)IBA 03/2017 - 06/2015
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2017 - 03/2010
2	Gabapentin (Neurontin)FDA LinkGeneric 01/2017 - 01/2003
2	sec-butyl-propylacetamideIBA 01/2017 - 09/2016
2	LipopolysaccharidesIBA 01/2017 - 04/2011
2	Lacosamide FDA Link 02/2015 - 05/2007
2	Sodium Channels (Sodium Channel)IBA 02/2015 - 02/2007
2	salicylhydroxamic acid (SHAM)IBA 04/2014 - 05/2004
2	Peptides (Polypeptides)IBA 05/2012 - 01/2011
2	Neuropeptide YIBA 04/2011 - 07/2008
2	NeurotensinIBA 04/2011 - 03/2009
2	Amino Acids FDA Link 09/2009 - 05/2007
2	SodiumIBA 03/2007 - 05/2004
2	2,2,3,3-tetramethylcyclopropane carboxamideIBA 01/2007 - 02/2002
2	GABA-A Receptors (GABA(A) Receptor)IBA 12/2006 - 06/2006
2	besonprodilIBA 03/2004 - 03/2004
2	conotoxin GVIBA 03/2004 - 03/2004
1	soticlestatIBA 01/2022
1	BenzodiazepinesIBA 12/2021
1	Glial Fibrillary Acidic ProteinIBA 12/2021
1	S-2-O-carbamoyl-1-o-chlorophenyl-ethanolIBA 01/2021
1	Meprobamate (Miltown)FDA LinkGeneric 01/2021
1	flupirtineIBA 01/2021
1	Voltage-Gated Sodium Channel BlockersIBA 11/2020
1	FenfluramineIBA 11/2020
1	1H-tetrazole (tetrazole)IBA 11/2020
1	Aminobutyrates (Aminobutyric Acid)IBA 07/2020

Therapy/Procedure

29	Therapeutics 01/2021 - 11/2002
5	Drug Therapy (Chemotherapy) 01/2019 - 12/2016
3	Analgesia 01/2019 - 02/2013
2	Intravenous Administration 01/2019 - 01/2017
2	Oral Administration 01/2019 - 05/2012
2	Polypharmacy 01/2018 - 01/2017